'DNA Diet' Tests Promise To Help Improve Your Health
Scientific approach: how can testing your DNA help you lose weight?
In the vastness of the Web, you can find a huge number of diets and diet plans for proper nutrition. More fiber, five servings of vegetables and fruits a day, for dinner - kefir, forget about butter. Sound familiar, but not very effective? The thing is that we are completely different, and therefore what suits one person may not be acceptable to another.
Genes know everything about you
Genes determine 70% of what who any person is. At the same time, 99.9% of our DNA coincides, and only 0.1% is responsible for all the differences that make each of us unique: hair color, eyes, predisposition to diseases, physical potential, features of appearance. Knowing this information, you can adjust your lifestyle so that you are in harmony with your own body.
In 2003, Nobel Prize winner James Watson completed a complete deciphering of the structure of human DNA ... Thanks to his research, about 20 thousand genes have been identified that are responsible for the predisposition to diseases, the characteristics of food, mental and physical behavior, that is, determine individual characteristics.
Out of 20 thousand, we, together with the laboratory of the Institute of Chemical Biology and fundamental medicine SB RAS and our colleagues from the companies MyGenetics and GrinDin have chosen for analysis and decided to focus your attention on those genes that carry the most important information about the characteristics of our body.
Genetic predisposition is not a diagnosis. What does the DNA report contain?
DNA testing does not determine your current state of health, it speaks about genetic predispositions to certain physiological conditions, helps to calculate risks, and also indicates a number of characteristic signs associated with nutrition and physical activity.
How does it work? Order a DNA test kit. Follow the instructions to collect the saliva and send in a sealed envelope by courier. Your DNA will be examined in the laboratory of the Institute of Chemical Biology and Fundamental Medicine of the SB RAS. This will take 3-4 weeks. You can find a detailed DNA report in your personal account or receive it by mail. It includes interpretation of results and professional guidance.
But let's see what's new you will be able to find out thanks to the DNA report and what the deviation of genes from the norm will tell you.
Gen FABP2 - fat assimilation
This gene encodes a protein that binds fatty acids in the intestine and promotes their active transport and assimilation. It has a high adaptability to saturated fats and provides capture and transport into the lymphatic system.
Why the mutation is dangerous: A mutation in the gene leads to an increase in the absorption of saturated fatty acids in the intestine and body weight gain.
Gene АDRB2 and TCF7L2 - sugar splitting
- ADRB2 encodes a protein that interacts with adrenaline and regulates the rate of sugar breakdown in muscles and liver. Why the mutation is dangerous: mutations in this gene lead to a decrease in the rate of consumption of carbohydrate reserves in liver cells and their conversion into fats.
- The TCF7L2 gene encodes a protein that is involved in the regulation of insulin secretion in the pancreas. Why mutation is dangerous: A mutation in this gene contributes to the development of insulin resistance and type 2 diabetes.
The results obtained on the basis of DNA research make it possible to determine the possibility of overweight, lactose intolerance, alcohol dependence, intestinal dysfunctions, salt-sensitive hypertension, disturbances in water-salt metabolism between the external and internal environments of the body.
GLUT2 gene - sensitivity to sweets
This gene encodes a protein that transports glucose across the cell membrane. Why the mutation is dangerous: in this gene, the mutation leads to a decrease in sensitivity to sugar and an increase in its consumption in food.
LCT gene - lactose perception
The LCT gene encodes a protein lactase, which is produced in a thin intestines and is involved in the breakdown of milk sugar. The original form of this gene is associated with a decrease in the activity of lactase synthesis with age. A common variant of the norm is associated with lactose intolerance. The presence of one polymorphism in the gene is favorable and leads to the acquisition of the ability to digest milk in adulthood.
Gene CD36 - recognition of fats
Encodes a protein that is involved in the recognition of fats in food and their absorption into intestines. Mutations in this gene lead to impaired perception of fatty acids and an increase in the amount of their consumption.
CYP1A2 gene - caffeine metabolism
The CYP1A2 gene encodes a protein that plays an important role in the detoxification of numerous compounds, including the metabolism of caffeine, and the more caffeine circulates in the blood, the higher risk of hypertension and myocardial damage. A mutation in this gene leads to a decrease in the metabolic rate of caffeine and an increase in the duration of circulation in the blood.
HLA-DQ2 gene - gluten intolerance
Encodes a protein involved in the recognition of self and foreign cells organism and foreign compounds. Located on the cells of the immune system. One of the variants of this protein binds tightly to gluten proteins, which leads to immunologicalreactions to gluten and celiac disease.
ADD1 gene - salt intake
ADD1 gene encodes a structural protein of the cell that is involved in transport sodium ions through the kidneys. Mutations in this gene lead to impaired sodium ion transport and the development of salt-sensitive hypertension.
APOA5 gene - triglycerides
The APOA5 gene encodes a protein that plays a role in changes in the concentration of triglycerides in the blood. Mutations in this gene lead to an increased risk of triglyceridemia and the development of obesity.
MC4R gene - satiety time
The MC4R gene encodes a protein that is involved in the regulation of metabolism, eating behavior and sexual desire ... Through this receptor, a signal is triggered to suppress hunger and reduce food intake. Mutations in this gene lead to excess food intake.
The need for vitamins
In some cases, the standard vitamin and mineral complex does not cover individual needs *. There are genetic markers that may indicate greater health benefits of certain micronutrients - vitamins and minerals - so it is possible that you should control the amount of these substances in your diet. A balanced diet that provides the optimal amount of vitamins and nutrients is an important part of good health.
Based on DNA analysis, one can judge about genetically determined characteristics of an organism. At the same time, the influence of external factors, such as the environment, allergies, acquired chronic diseases, cannot be taken into account in this report. However, they must be taken into account when implementing the recommendations. It is important that you understand this, regardless of whether you consider yourself to be absolutely healthy or know about any of your chronic diseases.
Based on all the recommendations, you can easily compose your balanced diet, adhering to which you can lose weight, gain weight or maintain your weight. In addition to this menu, rich in missing (at the genetic level) trace elements, nutrients, vitamins, will help you achieve not only external, but also internal changes in your body.
How to Diet?
- The safety of following the recommendations in this report depends on your initial health status.
- Before switching to an optimal DNA diet, it is necessary to consult a personal physician and, if necessary, an endocrinologist to exclude contraindications to the recommended diet.
- Your individual menu can be modified or supplemented by a qualified endocrinologist or nutritionist, taking into account the optimal DNA diet we have proposed.
- If your health condition does not allow you to start eating a genetically determined diet, begin a gradual transition to a DNA diet under the supervision of a qualified nutritionist or endocrinologist and your personal doctor.
- If you feel any deterioration in well-being while following the diet, you must promptly inform your doctor about it.